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Total Electronic Control Co Ltd
Flow Cytometer for the separation of multicellular organisms
Made in the UK by the Total Electronic Control Co Ltd, Hill Road, Fetcham KT22 9SZ.
Made to separate male and female Anopheles Mosquito L1 larvae for malaria research and reduction.
The RFP collected males are then released into the wild where they breed and produce future generations of sterile mosquito.
It is fully self contained with a 1 litre sample container and air pump to separate and collect larvae up to 2 a second.
Very simple to set up and use. It will collect any given volume from 10 to 990 larvae and display the total larvae count and the collected male larvae count.
It is a modular design. Each of the 6 parts can be easily separated for shipping by just unplugging the colour coded connectors. It can then be reassembled without the need of a ‘commissioning’ engineer.
Perfect for lab-based research and also large-scale field work.
I am an indigenous female and killed more than half a million people last year.
I am a transgenic male engineered with a genome to prevent future generations.
The Anopheles Mosquito is regarded as the most dangerous animal in the world and killed around 1000 children under 5 every day in 2022.
The World Health Organisation (WHO) produce an annual World Malaria report and the 2023 edition states that in 2022 there were 249 million cases of Malaria. 5 million more than 2021.
Two machines built for Imperial College are at The Liverpool School of Tropical Medicine where work is proceeding with CRISPR-Cas9 transgenic variation. The male larvae are harvested then released where they compete with the male population to result in fewer female offspring or life limited next generation mosquitoes.
The machine is ‘plug and play’ with a very simple instruction set. It does not need engineer installation and all parts are simple to fault find and replace if ever required.
The cost is less than a tenth of the alternative. It can separate and collect the chosen larvae at 2 a second.
The Total Electronic Control Ltd Hill Road, Fetcham, Surrey, KT22 9SZ.
Telephone: 00 44 07831 734707
teccoltd@outlook.com
Frequently Asked Questions
What is the Flow Cytometer for Multicellular Organisms?
The Flow Cytometer for Multicellular Organisms is a UK-developed instrument by Total Electronic Control Co Ltd, designed specifically for separating male and female Anopheles mosquito L1 larvae used in malaria research and reduction programs.
How does it work?
The system uses a gentle, low-voltage flow method to sort larvae based on fluorescent markers. Male larvae expressing RFP (Red Fluorescent Protein) are identified and collected automatically. The machine is fully self-contained, featuring a 1-litre sample container and air pump, capable of sorting up to two larvae per second.
What happens to the sorted larvae?
The collected male larvae are typically released into the wild, where they breed and generate sterile offspring, supporting mosquito population control and malaria reduction efforts.
How easy is it to use and maintain?
This machine is plug-and-play, requiring no installation engineer. It includes a simple instruction set, clear display of total and collected larvae counts, and easily replaceable components for straightforward maintenance.
What volumes can it handle?
It can process any selected volume from 10 to 990 larvae, displaying both the total count and male larvae collected for accurate data tracking.
Is the design portable and easy to ship?
Yes. The unit’s modular design allows its six main parts to be separated quickly using colour-coded connectors. It can be reassembled without a commissioning engineer, making it ideal for both laboratory and field-based research work.
Where is it used currently?
Two machines developed for Imperial College London are currently in use at the Liverpool School of Tropical Medicine, where they support research involving CRISPR-Cas9 transgenic mosquito variation to help reduce malaria transmission.
How does it compare to other systems?
This system costs less than one-tenth of comparable alternatives while offering reliable, high-speed sorting performance. Its simplicity, portability, and affordability make it an accessible solution for global research programs.
Who manufactures it and where?
All units are designed and manufactured in the United Kingdom by Total Electronic Control Co Ltd, Hill Road, Fetcham, KT22 9SZ.
How can I purchase or request more information?
For technical specifications, pricing, or demonstration requests, please contact Total Electronic Control Co Ltd through our website or email. Our team will be happy to provide detailed information and support your research needs.